Effects of Muscarinic Antagonists on Experimental Nasal Secretion in Guinea Pigs
نویسندگان
چکیده
منابع مشابه
Effects of muscarinic antagonists on experimental nasal secretion in guinea pigs.
The effects of muscarinic antagonists on acetylcholine (ACh)- and histamine-induced nasal secretion were investigated in guinea pigs. Inhalations of flutropium (0.01 to 0.3%) and atropine (0.03 to 0.3%) into the nasal cavities dose-dependently inhibited the nasal secretion induced by ACh. The inhibitory action of flutropium was slightly stronger than that of atropine. Inhalations of pirenzepine...
متن کاملTherapeutic analysis of organic acids on experimental dermatophytosis in guinea pigs
The purpose of this study was to determine the therapeutic efficacy of citric and tartaric acids on experimental dermatophytosis in guinea pigs. In this study, the susceptibility of Trichophyton mentagrophytes var. mentagrophytes to citric and tartaric acids was assessed using the macrodilution broth method. In the animal experiments, a cream consisting of the mixed acids was topically applied ...
متن کاملInfluence of estradiol administration on estrogen receptors of nasal mucosa: an experimental study on guinea pigs.
INTRODUCTION Some clinical trials revealed a correlation between increased serum estrogen and nasal symptoms or inflammatory changes in nasal mucosa. Estrogen receptors tend to be controlled by a negative feedback, to avoid a deleterious stimulus over several body functions while in hyperestrogenic periods. This study proposes a hypothesis where mechanisms regulating expression of estradiol rec...
متن کاملExperimental Pneumonia in Guinea Pigs
1. Anti-pneumotoxic sera prepared in rabbits or horses by immunization with sterile filtrates of the pneumotoxin, under certain conditions protect against the pneumonia caused by the intratracheal injections of mixtures of living pneumococci and toxic autolysates. 2. The protection against the development of pneumonia is heterologous, at least as regards Type I, Type II, viz.: an anti-autolysat...
متن کاملEffects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs.
The role of cysteinyl leukotrienes (cys-LTs) and thromboxane A(2) (TXA(2)) in guinea pig models of aspects of bronchial asthma was investigated. In a novel antigen (BSA)-induced asthmatic model using passively sensitized guinea pigs, pretreatment with varying doses of indomethacin controlled the ratio of followed lipid mediators, LTC(4)/D(4)/E(4) and TXB(2), in lungs of challenged guinea pigs. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1991
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)39923-8